Where the first book of the Sprawl-trilogy was very narrowly focused on Case, the band of runners he got pressed into, and the Straylight-run, the second book takes a vastly different approach: it follows the stories of Turner, a, uhm, freelance career-change agent, Bobby, the titular Count Zero and a wannabe-decker, and Marly, a former gallerist finding herself exceedingly gainfully employed.
Their stories do converge in the end, but it takes quite a while for the connections to become apparent.
What connects them all is that they have to deal, one way or the other, with the fall-out from the Straylight-run and the new entities hounding the Matrix.

It can be read on its own, especially since it is only very loosely connected to Neuromancer, but it would give context.